Orthopaedic emergencies

by Stephanie Roche, Kim Laubscher, Stefan van der Walt & Stephen Roche


Learning Objectives

  1. Red flags in the outpatient setting: infection, malignancy and spinal disorders.
  2. Red flags in the Orthopaedics ward: fat embolism, compartment syndrome, Paediatrics: non-accidental injury.

Orthopaedic red flags

Many orthopaedic problems can be managed in the primary care setting. To practice safely at this level of care, medical officers need to know which patients to investigate and follow-up and when to refer patients for urgent or emergency management.

Initial assessment includes a thorough history of the presenting complaint and medical history (particularly concerning trauma, cancer, immunosuppressive conditions or medications), and a musculoskeletal and neurological examination. The crucial warning signs on history and examination that suggest serious pathology and which might warrant referral or specialist advice, are listed in the table.

Clinical red flags
History:
Local Rapidly progressive symptoms
Red, hot swollen joint
Pain interrupting sleep
Systemic Loss of appetite
Loss of weight
Fever
Change in bowel or bladder function
Weakness or change in sensation
History of cancer
History of intravenous drug use
Immunosuppression
Examination Fever >38oC
Inability to bear weight on joint
Red/hot /swollen joint
Saddle anaesthesia
Lower motor neuron signs
Reduced anal tone
Bilateral upper motor neuron signs

Malignancy

Malignant tumours of soft tissue and bone should be excluded in all patients with a mass or lesion with any of the characteristics listed in the table. Imaging (ultrasound for soft tissue masses, radiograph for bony masses) and referral to a specialist should be the next step. See the specific chapter for more information.

Red flags for masses
Rapid growth
Pain
> 5cm diameter
deep to fascia

Infection

Primary septic arthritis and osteomyelitis are important differentials in patients presenting with musculoskeletal pain or swelling. Delay in diagnosis (even by hours) can result in progressive joint destruction. Importantly, obvious signs of inflammation may be absent in immunosuppressed patients, and investigations may be warranted in the absence of systemic signs. In immunocompetent patients, one or more of the following features listed in the table alongside are present.

Diagnosis

Differential diagnosis:

For treatment, please refer to the respective chapter on infections.

Red flags for infections
Systemic Temperature
Leukocytes
Respiratory rate
Heart rate
>38°C
>12 000 x 109/L
elevated
elevated
Orthopaedic Inability to weight bear
Blood results ESR
CRP
>40mm/ hr
elevated

Clinical pictures of swollen, warm, red, painful joints
Clinical pictures of swollen, warm, red, painful joints (Picture: Dr K Laubscher)

Spinal pathology

In addition to the general red flags mentioned at the beginning of the chapter, the following features may also suggest serious spinal pathology. Patients presenting with signs of cord compression or cauda equina syndrome (see figure below) need urgent referral to an orthopaedic or neurosurgical service.

Red flags for spinal disorders
History - Back pain in a patient < 20 or > 55 years of age.
- Previous history of cancer
- Immunosuppression
- Thoracic pain
- Pain at rest or at night
- Neurological fallout
- Structural deformity
Cord compression Upper motor neuron symptoms:
- Increased muscle tone
- Brisk reflexes
- Clonus
- Weakness
Cauda equina Lower motor neuron symptoms:
- Sphincter disturbance, bladder or bowel changes,
-gait abnormalities, saddle anaesthesia, sexual dysfunction, decreased tone or weakness of lower limbs, absent reflexes, diminished or absent anal wink test and a bulbocavernosus reflex
The cauda equina is usually located below L3
The cauda equina is usually located below L3 (Picture: Dr K Laubscher)

Fat embolism syndrome

Definition: Fat embolism is a rare, non- thrombotic embolism that is potentially fatal and has a mortality rate of 15%. It is a systemic dysfunction caused by the entry of fat into the circulation, most commonly from the bone marrow. The mechanism of entry into the systemic circulation is thought to be due to either a patent foramen ovale or via microembolism, where the fat particles are small enough to pass from the pulmonary arteries into the pulmonary veins. Patients typically develop fat embolism as a result of long bone fracture or orthopaedic surgery. It occurs 12 hours to 2 weeks following trauma or surgery. The diagnostic criteria in the following table can be used.

Management: Supportive treatment with frequent ICU admission is required.

Clinical features of fat embolism
Gurd and Wilson criteria:
2 major or 1 major and 4 minor criteria = FES
Major
  1. Petechial rash
  2. Respiratory symptoms plus bilateral signs with positive radiographic changes
  3. Cerebral signs unrelated to head injury or any other condition
Minor
  1. Tachycardia
  2. Pyrexia
  3. Retinal changes (fat or petechiae)
  4. Urinary changes (anuria, oliguria, fat globules)
  5. Sudden drop in haemoglobin level
  6. Sudden thrombocytopaenia
  7. High erythrocyte sedimentation rate
  8. Fat globules in the sputum

Compartment syndrome

Compartment syndrome results from increasing pressure in an anatomical compartment (typically muscle compartments divided by strong fascia), where the tissue pressure exceeds the vascular perfusion pressure. The tissue becomes ischaemic and infarction will occur without urgent intervention.

Clinical features:

Can occur after any form of injury, but most commonly associated with long bone fractures or other forms of trauma

The leg's anterior compartment is most frequently affected (e.g. after tibia fracture), but any compartment can be affected (e.g. hand or forearm).

Early symptoms include pain, paraesthesia and swelling. Often the pain is out of proportion to what is expected from the injury. These symptoms occur as venous pressure is exceeded. Late symptoms include the other Ps: paralysis, absent pulses, pallor and poikilothermia (or cold peripheries). These symptoms occur as arterial pressure is exceeded.

The diagnosis is clinical; the management is urgent fasciotomy.

Clinical picture of a forearm with multiple gunshot injuries and fasciotomy incisions. The dusky hand indicates compromised perfusion.
Clinical picture of a forearm with multiple gunshot injuries and fasciotomy incisions. The dusky hand indicates compromised perfusion. (Picture: Dr K Laubscher)

Deep vein thrombosis

Deep vein thrombosis (DVT) occurs when there is thrombus formation in one of the deep veins, typically of the lower limb or pelvis.

Thromboembolism to the pulmonary vasculature (pulmonary embolism) is the most feared complication and is potentially fatal. Importantly, Orthopaedic post-surgical patients are at a greater risk of DVT due to the nature of the operation ( hip and pelvic surgery, for example) and because these patients are often older and immobile.

Clinical features:

Diagnosis: Compression ultrasonography

Management: DVTs can mostly be prevented with early mobilisation, compression stockings and pharmacological prophylaxis. Treatment involves anticoagulation therapy with heparin and warfarin.

Non-accidental injury in a child

The red flags listed at the beginning of this chapter should also be applied to children. Every child with a painful or swollen joint should be assessed as to whether they appear systemically unwell or not, and the degree to which they can weight bear or use the affected limb. Orthopaedic and non-orthopaedic red flags are listed in the table below.

Management

Clear, accurate and thorough documentation of all findings, which may also include sketches. By law, all suspected child abuse must be reported to the relevant authorities ( police, social worker, and so on). See the specific chapter in the section on fractures in children for an approach to these patients.

Red flags for child abuse
Multiple fractures at different stages of healing.
Fractures other than the skull or clavicle in neonates (may occur during birth).
Severe skull fractures in children under 18 months.
Long bone fractures in infants not yet walking.
Digital fractures in children under three years.
Sternal, rib or scapula fractures (suggest high energy force).
Vertebral body fractures.
Metaphyseal corner fractures (occurs when a limb is pulled, twisted or shaken).
Epiphyseal separations
Inconsistent history, lack of witnesses for the incident or clinical findings inconsistent with the reported mechanism of injury..

Open fractures

Irrigate, stabilise and administer appropriate early antibiotics. See the chapter on ‘Orthopaedic Injuries’.

Clinical and radiological images of open fractures
Clinical and radiological images of open fractures (Picture: Dr K Laubscher)

References

Amboss. Nonthrombotic embolism, 2019.Available: https://www.amboss.com/us/ Department of Health. Standard Treatment Guidelines and Essential Medicines List for South Africa. (Cellphone application, most recently updated 2019)

Kearon C, Bauer KA, 2018. Clinical presentation and diagnosis of the nonpregnant adult with suspected deep vein thrombosis of the lower extremity. Available [Online in UpToDate]: https:// www.uptodate.com/contents/clinical- presentation-and-diagnosis-of-the- nonpregnant-adult-with-suspected-deep- vein-thrombosis-of-the-lower-extremity

Luqmani R, Joseph B, Robb J, Porter D. Textbook of orthopaedics, trauma and rheumatology. Elsevier Health Sciences, Dec 20, 2012.

Rasul AT, 2018. Acute compartment syndrome. Available: https://emedicine. medscape.com/article/307668- overview#a3

Scherl SA, 2019. Orthopedic aspects of child abuse. Available [Online in UpToDate]: https://www.uptodate.com/contents/ orthopedic-aspects-of-child-abuse

Stracciolini A, Hammerberg EM, 2018. Acute compartment syndrome of the extremities. Available [Online in UpToDate]: https://www.uptodate.com/ contents/acute-compartment-syndrome-of- the-extremities

Weinhouse G, 2019. Fat embolism syndrome. Available [Online in UpToDate]: https://www.uptodate.com/ contents/fat-embolism-syndrome